Chemistry 332 - Winter 1997

Chapter 9 - Carbonyl Compounds

New Skills

Knowledge - Level 1

know the terminology

acetal, hemiacetal, ketal, hemiketal, protecting group


Concepts - Level 2

understand how the polarity of the carbonyl group leads to nucleophilic addition reactions

recognize how acid or base catalysis assists nucleophilic addition reactions

recognize the relative reactivity expected for aldehydes or ketones
(steric hindrance / conjugation effects)



Applications - Level 3

be able to name various aldehydes and ketones

write products of oxidation or reduction reactions involving aldehydes or ketones

write products of nucleophilc additions to carbonyl compounds:

water --> hydrates
alcohols --> hemiacetals, acetals
amines --> imines
hydrides --> alcohols
organometallics --> larger alcohols (with a new C-C bond)



Analytical Skills - Level 4 & higher

write mechanisms for nucleophilic addition reactions, with acid or base catalysis

create a synthetic sequence to prepare a given target molecule,
especially including Grignard additions