Carey, pages 1189 - 1191 :
Problems 28.14 - 22
1. Sickle cell anemia is a genetic defect in the structure of hemoglobin,
in which just one amino acid is altered. One glutamic acid is replaced by
a valine. Describe why this change could be so serious for the protein tertiary
structure.
Suggest a possible code in the DNA that might have been altered
in order to read Val instead of Glu.
2. Some codons can be deduced from simple homopolynucleic acids, e.g.,
poly-A. Explain.
Identify the four amino acid codes that can be deduced this
way.
