Chem 335 - Winter 1999 -
Organic Chemistry II know the terminology:
acetal, hemiacetal, ketal, hemiketal
alpha-carbon, deuterium exchange
cyanohydrin, Wittig reagent, ylid, 1,3-dithiane
imine, oxime, hydrazone
haloform, Baeyer-Villager oxidation
Clemmensen reduction, Wolff-Kishner reduction
McLafferty rearrangement
understand how the polarity of the carbonyl group leads to nucleophilic addition reactions
recognize how acid or base catalysis assists nucleophilic addition reactions
recognize the relative reactivity expected for aldehydes
or ketones
(steric hindrance / conjugation effects)
be able to name various aldehydes and ketones
write products of oxidation or reduction reactions involving aldehydes or ketones
recognize appropriate reagents to carry out a specific reaction
write products of nucleophilc additions to carbonyl compounds:
water --> hydrates
alcohols --> hemiacetals, acetals
thiols --> thioacetals or 1,3-dithianes
amines --> imines
hydrides --> alcohols
organometallics --> larger alcohols (with a new C-C bond)
Wittig reagents --> alkenes
write mechanisms for nucleophilic addition reactions, with acid or base catalysis
write mechanisms for alpha-substitution or enol reactions
create a synthetic sequence to prepare a given target molecule