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Organic
Chemistry II
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Professor
Carl C. Wamser
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Chapter
18 Skills
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Enols & Enolates
Knowledge - Level 1
Terminology:
aldol condensation, mixed aldol
Michael reaction, conjugate addition
Robinson annulation
Concepts - Level 2
recognize the nucleophilicity of carbonyl alpha-anions
recognize the special reactivity of conjugated enones towards nucleophiles
(conjugate or Michael addition)
Applications - Level 3
predict products of aldol ractions including cases of intramolecular
or mixed reactions
predict products from Michael additions
illustrate or identify the Robinson annulation reaction sequence
Analytical Skills - Level 4
write mechanisms for aldol reactions
write mechanisms for alpha-substitution reactions
write mechanisms for conjugate addition reactions
Synthetic Skills - Level 5
create a synthetic sequence to prepare a given target molecule,
especially using aldol condensation
