complex_down_regulation/csr_framework_grammar.htm

CSR framework and the grammar of regulation

Dec. 1, 2001

Three alternative views of Reynold's CSR Framework

Reynold's view, with short explanation:

STRESS

Low

High

Low

DISTURBANCE

High

C - competitors

rapid growth

detail

S - stress

low nutrients or light

detail

R - ruderal

adapted to mixed environment

detail

 

 

Stress environment, description from Arrow et al. ****

STRESS

controllable

uncontrollable

predictable

PREDICTABILITY

unpredictable

cells create their own stress through nutrient depletion or light attenuation

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cells need to adapt to stress or try to innovate

 

cells can't predict the continual disturbances

 

 

 

 

Hypothesized regulatory grammar

ATTRACTORS

 

simple, point attractors

 

several basins with sharp ridges

 

long periodic attractors and broad, shallow basins