algae/??/short-term-regulation-of-PS.htm

Short term regulation of energy distribution to photosystems and the potential role of ROS

1. The balance hypothesis

Diagram fo the balance hypothesis

 

Regulation of states and flow of e- from PS2 to PS1 - achieving a balance

Raven (1984)

State 1- State 2 transition could have a role in balancing the redox state of the photosystems and increasing production of ATP when excess reductant is being produced

State 1 occurs in darkness or illumination conditions that over excite RC1. The cell responds by favoring the distribution toward RC2 to compensate.

Sate 2 occurs at high light or other conditions which over excite RC2. The distribution favors RC1.

e- flow can be allocated to:

ferredoxin to NADP+ (non-cyclic e- flow)

O2 (pseudocyclic electron flow - the Mehler reaction)

back to cytochrome b6/f complex (cyclic electron flow)

Falkowski and Raven (1997)

pg 91 based on low photon flux, less light is dissipated than would be expected from a pure Poisson function, postulate exitation transfer between reaction centers. An exciton might wander around until it finds an open reaction center.

Down regulation

??

Fujita et al 1994 - in Bryant

short term adaptation by state transition (minutes)

PS1:PS2 ratio changes over longer periods of time (days)

proportion of non-cyclic to cyclic may be needed to support ATP needed for ion uptake (such as HCO3-) or osmoregulation

energy distribution from PBS is called the state transition

PBS light energy goes to PS2 then PS1 by spillover

in higher plants LHC II distributes energy to PS1 and PS2 depending on its phosphorylation status

non-phosphorylated LHC II - most energy to PS2

phosphorylated LHC II - more energy to PS1

hypothesized - protein kinase is activated by reduced PQH2 (or Cytb6/f), activation causes more energy to be distributed to PS1 and balances that redox level of the PQ/PQH2 pool

dephosphorylation of LHC II is by a constitutive phosphatase - requiring constant phosphorylation to keep LHC II in state 2

could be related to redox state of Cytb6/f complex also

Kana, Geider and Critchley 1997

balanced energy flow between PS2 and PS1

redox poise of PQ pool has transcription control of cab gene which directs synthesis of antenna pigment protein LHC II

call this the regulatory ratio

pigment losses and specifically, the continual turnover of the D1 protein has been argued to be part of the normal regulatory system

model that goes to optimal energy flow between PS2 and PS1

 

2. Mechanisms that produce H2O2 and ROS are parallel to the balance hypothesis mechanisms

Mehler has already been shown to be involved in regulation

Schreiber & Neubauer 1990

down regulation of PSII quantum yield is expressed by qN - non-photochemical quenching

Mehler-Peroxidase reaction, that allows non-assimilatory e- flow, is responsivle for increasing the transmembrane delta pH

when qN is increased (high transmembrane delta pH) the quantum yield is lower

one of the two major ways photosynthesis is controlled, the other being the rate limiting step at PQ to cytb6/f

mechanism for producing H2O2

Polle 1996

Mehler reaction

may increase if the utilisation of NADPH is blocked and NADP+ is not available

delta pH across membrane leads to down regulation of photosynthesis

Cohen v738

there are many sources of ROS that should occur in any cell, whether it's a cyanobacterium or not

including leakage from mitochondrial electron transport, redox cycling that includes Fe and Cu and lipid peroxidation reactions

Gonzalez-Flecha and Demple v899

summarizes hydrogen peroxide concentrations in many systems

bacteria (E. coli) and plant cells have higher steady steate amount than most mammalian cells

quinone pool is one source

thus the mechanisms that produce H2O2 and other ROS in cells are common, expect that they have similar regulatory effect (part 4)

 

 

 

 

 

 

3. Cyanobacteria have a dual function membrane

the dual function membrane has respiration and photosynthetic processes that need to be coordinated

Obinger et al 1998

cyanobacteria were the first to make O2 and among the first to be affected by it

dual-function photosynthetic-respiratory assembly

contains thylakoid Cytb6/f and another, immunologically different, mitochondria-like multi-component dehydrogenase and cytochrome bc1 complex.

cytosolic Fe-SOD and thylakoid bound Mn-SOD help scavenge O2-

 

4. Proposed role for H2O2 and ROS in regulation based on observations in cyanobacteria and other systems

 

SOD in cyanobacteria respond to SO -

 

good second messenger

Gilbert - creation is inevitable side product of reaction and mechanisms exist to destroyed rapidly