Of 1,000,000 conceptions
150,000 Spontaneous abortions
75,000 chromosome abnormalities
39,000 trisomics (3,510 trisomy 21)
13,500 XO
12,750 triploids
4,500 tetraploids
5,250 others
850,000 Live births
17,000 perinatal deaths
833,000 children
5,165 chromosome abnormalities
1,849 sex chromosome aneuploids
1,183 autosomal trisomics
42 trisomy 13
100 trisomy 18
1041 trisomy 21
758 balanced Robertsonian translocations
758 balanced reciprocal translocations
117 inversions
500 unbalanced structural aberrations
Ref: Mutation Research 61; K. Sankaranarayanan