Chem 336 - Spring 2002
Organic Chemistry III
Dr. Carl C. Wamser
In order to do this pre-quiz, you must log in to the class WebCT site.
This pre-quiz must be submitted via WebCT before Wednesday morning, April 17, 8:30 am.
1. The carboxyl derivative most reactive towards nucleophilic substitution is
* 1) acyl halide
2) acid anhydride
3) ester
4) amide
5) nitrile
2. Saponification is a term describing
1) Fischer esterification
2) Grignard additions
3) acid-catalyzed amide hydrolysis
4) acid-catalyzed ester hydrolysis
* 5) base-promoted ester hydrolysis
3. Hofmann rearrangement of benzamide would give
1) benzyl amine
* 2) aniline
3) phenol
4) phenylethylamine
5) none of the above
4. A carboxyl derivative that could be made from 1-bromobutane by an SN2 reaction is
1) butanoic acid
2) pentanoic acid
3) butanenitrile
* 4) pentanenitrile
5) 1-butanol
5. An amine that would not react with acetyl chloride to make an amide is
1) aniline
2) benzyl amine
3) methylamine
4) dimethylamine
* 5) trimethylamine