Chem 336 - Spring 2000
Organic Chemistry III
Dr. Carl C. Wamser

Molecule of the Week #2

Haloperidol or Haldol

Hello Dr. Wamser,

I think the molecule of the week is Haloperidol with a molecular formula of C21 H23 Cl F N O2 and a molecular weight of 375.8696 g/mol.

Synonyms: Haldol; 4-[4-(p-chlorophenyl)-4-hydroxypiperidino]-4'-fluorobutyrophenone; gamma-(4-(para-Chlorophenyl)-4-hydroxypiperidino)-para'-fluorobutyrophenone; Serenace.

Haloperidol is a tranquilizer and a antipsychotic used to treat nervous, mental, and emotional conditions. The drug is useful in treatment of tics and vocal utterances of patients who have Tourette's Disorder. It can also be used to treat children who are combative, possess explosive hyperexcitability, and hyperactive children who show excessive motor activity. Side effects include convulsions, fast heartbeat, fever, and high or low blood pressure.

Sources:

http://www.chemfinder.com

http://microscopy.fsu.edu/pharmaceuticals/pages/haloperidol.html

Lisette Oei