The lehman lab at portland state university

I am interested in molecular evolution and the biochemistry of catalytic RNAs (ribozymes). Research in my lab utilizes powerful in vitro evolution techniques to discover RNA sequences with new or improved functions, for example, in regard to RNA-metal ion interactions. We are particularly keen to use these techniques to test fundamental evolutionary hypotheses, such as the antiquity of recombination.

My teaching at PSU includes the third term of general biochemistry, general chemistry, a non-majors course on the origins of life, and a graduate course on prebiotic chemistry. For updated class information, click on the teaching button above.

For more information on research in the Lehman Lab at PSU, click on the research button above. Perspective postdocs, graduate students, and undergraduates interested in performing research in evolutionary biochemistry can contact me by email or in person in 422 Science Building Two (STRC). For information on Ph.D. (or B.S. and M.S.) degree programs in chemistry at Portland State, click on the Chemistry Department banner below.

The Lehman lab is a member of the PSU Center for Life in Extreme Environments (CLEE).

The RNA world is alive and well!

Most recent publications:

Vaidya N, Walker SI, Lehman N (2013). Recycling of informational units leads to selection of replicators in a prebiotic soup. Chemistry & Biology 20: 241-252. 

Vaidya N, Manapat ML, Chen IA, Xulvi-Brunet R, Hayden EJ, Lehman N (2012). Spontaneous network formation among cooperative RNA replicators. Nature 491: 72-77. 

Lehman N, Diaz Arenas C, White WA, Schmidt FJ (2011). Complexity through recombination: From chemistry to biology. Entropy 13: 17-37.
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