Chem 492 / 592 Biochemistry iii portland state university

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Chem 492 / 592

Biochemistry iii

portland state university

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Nucleic acids and biological information flow

This course is the third course in a three course series in biochemistry and is taught during Spring quarter. This course focuses on the biochemical aspects of biological information flow, including nucleotide biosynthesis, DNA replication, RNA transcription, and protein translation. Students must have completed Chem 490 and Chem 491 prior to enrolling in Chem 492. I will expect all students to be completely comfortable with the material from these prior two courses. Grades in Chem 492 is based on two midterm exams, one final, and five short writing assignments. You may receive graduate credit (Chem 592) if you complete 10-page report in addition to the other assignments in the course.

More information regarding the course may be found from the syllabus. The links below give you a PDF files containing the syllabus for the quarter indicated. In order to view and download these files, you need Acrobat reader (You may obtain it free from: Adobe.)

Here is the Spring, 2011 term syllabus:

Chem492_Sp11_SYLv.pdf updated 3/28/11

Course materials for Chem492 is available for downloading below. These files may change from time-to-time, so make sure to check back frequently for up-to-date information.

Reading Assignments

due April 4, 2011: Crick&Watson_1954.pdf

due April 13, 2011: Matrick_ea_2008.pdf

due May 2, 2011: Changela_et_al_2001.pdf

due May 16, 2011: Kamtekar_ea_2006.pdf

due June 1, 2011: Kruger_et_al_1982.pdf

Other Files to Download:

Primer on Information Theory: Info_Theory.pdf

Sample Writing Assignment: examplepaper.pdf

Possible base pairs: RNABasePairs.pdf

Link to DNA replication movie: click here

Lecture Slides in PDF format: