Of 1,000,000 conceptions

150,000 Spontaneous abortions

75,000 chromosome abnormalities

39,000 trisomics (3,510 trisomy 21)

13,500 XO

12,750 triploids

4,500 tetraploids

5,250 others

850,000 Live births

17,000 perinatal deaths

833,000 children

5,165 chromosome abnormalities

1,849 sex chromosome aneuploids

1,183 autosomal trisomics

42 trisomy 13

100 trisomy 18

1041 trisomy 21

758 balanced Robertsonian translocations

758 balanced reciprocal translocations

117 inversions

500 unbalanced structural aberrations

 

Ref: Mutation Research 61; K. Sankaranarayanan